Kidney Disease Program

Metabolism/Excretion

Moderately dialyzable, 20-50%

Plasma Protein Binding %

6-15

Dose For Normal Renal Function

25-50 mg/kg/day q6h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

5-10 mg/kg dose q8h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

5-10 mg/kg dose q12h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

5-10 mg/kg dose q24h

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 5-10 mg/kg dose q24h after dialysis

Supplement For Dialysis [Recommendation Level]: Pd

PD: 5-10 mg/kg dose q24h

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: Not applicable, [B]