Kidney Disease Program

Metabolism/Excretion

Dialyzable

Plasma Protein Binding %

33-50

Dose For Normal Renal Function

30 mg/kg/day q12h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

15 mg/kg dose q12h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

15 mg/kg dose q24h

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 15 mg/kg dose q24h

Supplement For Dialysis [Recommendation Level]: Pd

PD: 15 mg/kg dose q24h

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: Not applicable, [D]