Kidney Disease Program

Metabolism/Excretion

Not dialyzable

Plasma Protein Binding %

85-90

Dose For Normal Renal Function

50-100 mg/kg/day q12-24h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

All doses q24h

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 50 mg/kg/dose q24h

Supplement For Dialysis [Recommendation Level]: Pd

PD: 50 mg/kg/dose q24h

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: 50 mg/kg dose q24h, [B]