Ceftizoxime

Plasma Protein Binding %
 
28-50
 
Dose For Normal Renal Function
150-200 mg/kg/day divided q6-8h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
50 mg/kg dose q8h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
50 mg/kg dose q12h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
50 mg/kg dose q24h
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 50 mg/kg dose q24h after dialysis
Supplement For Dialysis [Recommendation Level]: Pd
PD: 50 mg/kg dose q24h, or IP: LD 250 mg/L, maint 125 mg/L
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 50 mg/kg dose q8h, [B]