Metabolism/Excretion
50-100% dialyzable
Dose For Normal Renal Function
75-150 mg/kg/day q8h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
50 mg/kg dose q12h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
50 mg/kg dose q24h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
50 mg/kg dose q48h
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 50 mg/kg dose q48h, give on dialysis days after hemo run
Supplement For Dialysis [Recommendation Level]: Pd
PD: 50 mg/kg dose q48h, IP: LD: 250 mg/L, then 125 mg/L maint
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 50 mg/kg q12h, [A]