Kidney Disease Program

Metabolism/Excretion

63% removed by dialysis

Plasma Protein Binding %

60-70

Dose For Normal Renal Function

14 mg/kg/day q12h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

7 mg/kg dose q24h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

7 mg/kg dose q24h

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 7 mg/kg dose q24h

Supplement For Dialysis [Recommendation Level]: Pd

PD: 7 mg/kg dose q24h

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: Not applicable, [D]