Metabolism/Excretion
Moderately dialyzable, 20-50%
Dose For Normal Renal Function
50-100 mg/kg/day q8h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
25 mg/kg dose q12h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
25 mg/kg dose q24h
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 25 mg/kg dose q24h
Supplement For Dialysis [Recommendation Level]: Pd
PD: 25 mg/kg dose q24h, IP: LD: 500 mg/L, then 125 mg/L maint
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 25 mg/kg q8h, [A]