Metabolism/Excretion
20-24 hr T1/2 in renal failure
Dose For Normal Renal Function
30 mg/kg/day q12h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
15 mg/kg q24h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
15 mg/kg q36h
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 15 mg/kg q24h
Supplement For Dialysis [Recommendation Level]: Pd
PD: 15 mg/kg q36h
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Not applicable, [D]