Kidney Disease Program

Metabolism/Excretion

Moderatelydialyzable, 20-50%

Plasma Protein Binding %

Dose For Normal Renal Function

20-40 mg/kg/day q8-12h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

50%

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 50%, supplemental dose post hemo run needed

Supplement For Dialysis [Recommendation Level]: Pd

PD: 50%

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: Not applicable, [B]