Amikacin

Plasma Protein Binding %
 
Minimal
 
Dose For Normal Renal Function
5-7.5 mg/kg dose q8h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
q12-18h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
q18-24h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
q48-72h
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 5 mg/kg as indicated by serum concentrations
Supplement For Dialysis [Recommendation Level]: Pd
PD: 5 mg/kg as indicated by serum concentrations, or IP: LD: 25 mg/L, maint 12 mg/L
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 7.5 mg/kg q12h, monitor serum concentrations, [A]