Kidney Disease Program

Metabolism/Excretion

Partial hepatic metabolism, 45% excreted unchanged in urine

Plasma Protein Binding %

Dose For Normal Renal Function

0.015-0.1 mg/kg dose q6-24h, max 10 mg/day

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

100%

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: Not applicable

Supplement For Dialysis [Recommendation Level]: Pd

PD: 100%

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: 100%, Bumetanide 1 mg = 40 mg furosemide, [D]