Amiodarone

Metabolism/Excretion
Hepatic via P450
Plasma Protein Binding %
 
96
 
Dose For Normal Renal Function
Oral: 10-15 mg/kg/day load, 5 mg/kg/day maintenance; IV: 5-10 mg load, 5-15 mg/kg/min
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
100%
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 100%
Supplement For Dialysis [Recommendation Level]: Pd
PD: 100%
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 100%, [D]