Metabolism/Excretion
Liver, glucuronide conjugation; eliminated in urine as glucuronide conjugate
Dose For Normal Renal Function
Consult pediatric reference; doses vary upon indication
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
100%
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 100%
Supplement For Dialysis [Recommendation Level]: Pd
PD: 100%
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 100%, titrate to effect, PO/IV vehicle contains propylene glycol, monitor s/s of toxicity, [B]