Metabolism/Excretion
Excreted in urine, removable by hemodialysis
Dose For Normal Renal Function
Children >6 yo: 0.07 mg/kg dose up to 5 mg; 5-40 mg/day q12-24h adult dose
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
50%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
50%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
25%
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 25%
Supplement For Dialysis [Recommendation Level]: Pd
PD: 25%
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 50%, [D]