Metabolism/Excretion
Hepatic, 93% renally excreted
Dose For Normal Renal Function
600 mg/m2 dose q12h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
No more than 600 mg/m2/day
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
No more than 600 mg/m2/day
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: No more than 600 mg/m2/day
Supplement For Dialysis [Recommendation Level]: Pd
PD: No more than 600 mg/m2/day
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 100%, monitor serum concentrations when possible, not dialyzable, [D]