Thioguanine

Metabolism/Excretion
Extensive liver metabolism by methylation of thioguanine to 2-amino– methylthioguanine, metabolites excreted in urine ~40%
Plasma Protein Binding %
 
Unknown
 
Dose For Normal Renal Function
Refer to individual protocols
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
100%
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: No data
Supplement For Dialysis [Recommendation Level]: Pd
PD: No data
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 100%, [D]