Kidney Disease Program

Metabolism/Excretion

Hepatic, >95% drug excreted in urine

Plasma Protein Binding %

67 (albumin)

Dose For Normal Renal Function

Consult pediatric reference

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

50%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

50%

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 50%

Supplement For Dialysis [Recommendation Level]: Pd

PD: 50%

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: 50%, [D]