Kidney Disease Program

Metabolism/Excretion

Hepatic, 75% renally excreted, 20% removed dialysis, CrCl 13 ml/min T1/2 43 hr

Plasma Protein Binding %

55 (albumin)

Dose For Normal Renal Function

Consult pediatric reference

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

50%

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 50%

Supplement For Dialysis [Recommendation Level]: Pd

PD: 50%

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: N/A, [D]