Carbamazepine

Metabolism/Excretion
Hepatic
Plasma Protein Binding %
 
75-90 (mainly AAG)
 
Dose For Normal Renal Function
10-20 mg/kg/day q8-12h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
75%
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 75%
Supplement For Dialysis [Recommendation Level]: Pd
PD: 75%
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 75%, monitor serum concentrations, [B]
References
Taketomo, Hodding, Kraus. Pediatric Dosage Handbook, 13th edition. Lexi-Comp, 2006.