Enoxaparin

Metabolism/Excretion
40% excreted in urine; Cl decreased by 30% if CrCl <30
Plasma Protein Binding %
Minimal
Dose For Normal Renal Function
<2 mo: prophylaxis, 0.75 mg/kg dose q12h, treatment 1.5 mg/kg dose q12h; >2 mo: prophylaxis, 0.5 mg/kg dose q12h, 1 mg/kg q12h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
70%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
50% q24h
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 50%
Supplement For Dialysis [Recommendation Level]: Pd
PD: 50%
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 70%, follow Xa levels, adjust dosage per Pediatric Dosage Handbook, [B]