Cidofovir

Metabolism/Excretion
Metabolized intracellularly, eliminated by renal tubular secretion and glomerular filtration
Plasma Protein Binding %
 
<6
 
Dose For Normal Renal Function
Adenovirus: 1 mg/kg dose 3/week; CMV: Induction 5 mg/kg dose IV one time, maintenance 3mg/kg dose once weekly
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
Avoid, no data
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
Avoid, no data
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
Avoid, no data
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: Avoid, no data
Supplement For Dialysis [Recommendation Level]: Pd
PD: Avoid, no data
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Avoid, if have to use give 2 mg/kg weekly, [B]