Metabolism/Excretion
Hepatic, renally excreted, 50-100% dialyzable
Dose For Normal Renal Function
10-15 mg/kg dose q4-6h or 60-100 mg/kg/day q6hfor anti-inflammatory
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
Avoid
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: Give after dialysis
Supplement For Dialysis [Recommendation Level]: Pd
PD: Avoid
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 100%, monitor levels if possible, [D]