Kidney Disease Program

Metabolism/Excretion

50-100% dialyzable

Plasma Protein Binding %

10-15

Dose For Normal Renal Function

Treatment: 10-15 mg/kg/day q12-24h; Prophylaxis: 10 mg/kg/day q24h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

100%

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 100%, give after dialysis

Supplement For Dialysis [Recommendation Level]: Pd

PD: 100%

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: 100%, [D]