Kidney Disease Program

Metabolism/Excretion

5-20% dialyzable

Plasma Protein Binding %

20-30

Dose For Normal Renal Function

15-25 mg/kg/day q24h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

15-25 mg/kg dose q36h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

15-25 mg/kg dose q48h

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 15-25 mg/kg dose q48h

Supplement For Dialysis [Recommendation Level]: Pd

PD: 15-25 mg/kg dose q48h

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: 100%, [D]