Kidney Disease Program

Metabolism/Excretion

Hepatic, 41% urine

Plasma Protein Binding %

97 (albumin)

Dose For Normal Renal Function

70 mg/m2 (max 70 mg) 1 first day, then 50 mg/m2 (max 50 mg) q24h

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29

100%

Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10

100%

Supplement For Dialysis [Recommendation Level]: Ihd

IHD: 100%

Supplement For Dialysis [Recommendation Level]: Pd

PD: 100%

Supplement For Dialysis [Recommendation Level]: Crrt

CRRT: 100%, adjust for hepatic impairment, [D]