Caspofungin

Metabolism/Excretion
Hepatic, 41% urine
Plasma Protein Binding %
 
97 (albumin)
 
Dose For Normal Renal Function
70 mg/m2 (max 70 mg) 1 first day, then 50 mg/m2 (max 50 mg) q24h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
100%
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
100%
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 100%
Supplement For Dialysis [Recommendation Level]: Pd
PD: 100%
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 100%, adjust for hepatic impairment, [D]