Ampicillin/Sulbactam

Plasma Protein Binding %
 
Amp: 28, Sulb: 38
 
Dose For Normal Renal Function
100-200 mg/kg/day q6h of ampicillin portion
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 30-50
35-50 mg/kg dose q8h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 10-29
35-50 mg/kg dose q12h
Adjustment For Renal Function Gfr, Ml/Min/1.73M2 <10
35-50 mg/kg dose q24h
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: 35-50 mg/kg dose q24h
Supplement For Dialysis [Recommendation Level]: Pd
PD: 35-50 mg/kg dose q24h, or IP: LD 1 g/L, maint 100 mg/L
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 35-50 mg/kg dose q8h, [B]