Excreted Unchanged %
Hepatic
Half-Life (Normalesrd) Hours
10-19/No data
Plasma Protein Binding %
90-92
Volume Of Distribution L/Kg
14-21
Dose For Normal Renal Function
1-2 mg q8-12h
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: None, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: None, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50, [D]
References
Froemming JS, Lam YW, Jann MW, Davis CM. Pharmacokinetics of haloperidol. Clin Pharmacokinet. 1989; 17: 396-423. [PMID: 2689040]
Toxicity Notes
Hypotension, excessive sedation.