Excreted Unchanged %
Hepatic
Half-Life (Normalesrd) Hours
10-20/No data
Plasma Protein Binding %
35-50
Volume Of Distribution L/Kg
3-4
Dose For Normal Renal Function
500 mg qhs
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
Avoid [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
Avoid [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: Avoid, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: Avoid, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Not applicable
References
Yell RP. Ethchlorvynol overdose. Am J Emerg Med. 1990; 8: 246-50. [PMID: 2331266]
Toxicity Notes
Removed by hemoperfusion. Excessive sedation.