Excreted Unchanged %
45-60
Half-Life (Normalesrd) Hours
3.5-5.8/11.3
Plasma Protein Binding %
70
Volume Of Distribution L/Kg
0.42-0.57
Dose For Normal Renal Function
0.2-0.4 mg/kg
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
75% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
50% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
50% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: Not applicable, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: Not applicable, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50, [D]