Cholestyramine

Excreted Unchanged %
None
Half-Life (Normalesrd) Hours
Not absorbed
Plasma Protein Binding %
None
Volume Of Distribution L/Kg
None
Dose For Normal Renal Function
4.0 g q4-6h
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: None, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: None, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 100%, [D]
References
Silverberg DS, Iaina A, Reisin E, Rotzak R, Eliahou HE. Cholestyramine in uraemic pruritus. Br Med J. 1977; 1: 752-3. [PMID: 322794]
Toxicity Notes
Hyperchloremic acidosis.