General Toxicity Notes
May aggravate azotemia, Na+ retention, glucose intolerance, hypertension.
Half-Life (Normalesrd) Hours
5.5/No data
Plasma Protein Binding %
65
Volume Of Distribution L/Kg
1.4
Dose For Normal Renal Function
0.5-9.0 mg q24h
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: No data, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: Dose for GFR <10, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 100%, [D]