General Toxicity Notes
May cause excessive sedation in ESRD.
Half-Life (Normalesrd) Hours
14/No data
Plasma Protein Binding %
98
Volume Of Distribution L/Kg
No data
Dose For Normal Renal Function
No data
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: Dose for GFR <10, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: Dose for GFR <10, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Not applicable
References
Richards DM, Brogden RN, Heel RC, Speight TM, Avery GS. Oxatomide. A review of its pharmacodynamic properties and therapeutic efficacy. Drugs. 1984; 27: 210-31. [PMID: 6200290]