Excreted Unchanged %
No data
Half-Life (Normalesrd) Hours
0.3-0.5/Unchanged
Plasma Protein Binding %
No data
Volume Of Distribution L/Kg
0.7
Dose For Normal Renal Function
0.5-2.0 ng/kg/min for 5-12 h
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [A]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [A]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
50% [A]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: None, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: None, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50, [D]
References
Hildebrand M, Krause W, Fabian H, Koziol T, Neumayer HH. Pharmacokinetics of iloprost in patients with chronic renal failure and on maintenance haemodialysis. Int J Clin Pharmacol Res. 1990; 10: 285-92. [PMID: 1706685]