Excreted Unchanged %
No data
Half-Life (Normalesrd) Hours
12/No data
Plasma Protein Binding %
99
Volume Of Distribution L/Kg
2.4
Dose For Normal Renal Function
50 mg tid
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: None, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: Dose for GFR <10, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Not applicable
References
FitzGerald GA. Dipyridamole. N Engl J Med. 1987; 316: 1247-57. [PMID: 3553945] / Mahony C, Wolfram KM, Cocchetto DM, Bjornsson TD. Dipyridamol kinetics. Clin Pharmacol Ther. 1982; 31: 330-8. [PMID: 7060316]
Toxicity Notes
Adds to uremic platelet defect.