Excreted Unchanged %
No data
Half-Life (Normalesrd) Hours
1.2
Plasma Protein Binding %
No data
Volume Of Distribution L/Kg
0.08
Dose For Normal Renal Function
30 U over 2-5 min
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: Avoid, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: Avoid, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50, [D]
Toxicity Notes
Enhances bleeding in patients predisposed to bleed because of CKD.