Excreted Unchanged %
No data
Half-Life (Normalesrd) Hours
0.5
Plasma Protein Binding %
No data
Volume Of Distribution L/Kg
0.1
Dose For Normal Renal Function
60 mg over 1 h, then 20 mg/h for 2 h
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: No data, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: No data, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50, [D]
Toxicity Notes
Do not give within 10 days of surgery or kidney biopsy.