Excreted Unchanged %
No data
Half-Life (Normalesrd) Hours
3.8/No data
Plasma Protein Binding %
92
Volume Of Distribution L/Kg
0.08
Dose For Normal Renal Function
90 mg SQ bid
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [B]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: No data, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: No data, [D]
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dialysis rate must be at least 35 mL/min, [D]
Toxicity Notes
No data in renal insufficiency. Manufacturer reports no effect of reduced renal function with CrCl >35 mL/min.