Half-Life (Normalesrd) Hours
10
Plasma Protein Binding %
<4
Volume Of Distribution L/Kg
No data
Dose For Normal Renal Function
200 mg q24h
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% q48-96h [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% q96h [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: Dose after dialysis, [D]
Supplement For Dialysis [Recommendation Level]: Pd
PD: No data
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Capsule: 200 mg q48h; solution: 120 mg q24h, [D]