Half-Life (Normalesrd) Hours
0.5/No data
Plasma Protein Binding %
No data
Volume Of Distribution L/Kg
0.11-0.26
Dose For Normal Renal Function
250-500 mg q12h
Adjustment For Renal Failure Method
I
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
q12h[D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
q24h[D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
q36-48h[D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: None
Supplement For Dialysis [Recommendation Level]: Pd
PD: None
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50, [D]
Toxicity Notes
CNS toxicity.