Half-Life (Normalesrd) Hours
2/No data
Plasma Protein Binding %
No data
Volume Of Distribution L/Kg
No data
Dose For Normal Renal Function
1.0 g q24h
Adjustment For Renal Failure Method
I
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
q24h[A]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
q24h[A]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
q48h[A]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: Give dose after HD only
Supplement For Dialysis [Recommendation Level]: Pd
PD: None
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: 5 mg/kg q24h, [D]
References
Lehmann CR, Garrett LE, Winn RE, Springberg PD, Vicks S, Porter DK, et al. Capreomycin kinetics in renal impairment and clearance by hemodialysis. Am Rev Respir Dis. 1988; 138: 1312-3. [PMID: 2462388]
Toxicity Notes
Nephrotoxic. Potentiates neuromuscular blockade.