Azithromycin

Excreted Unchanged %
6-12
Half-Life (Normalesrd) Hours
10-60/No data
Plasma Protein Binding %
8-50
Volume Of Distribution L/Kg
18
Dose For Normal Renal Function
250-500 mg q24h
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100%[A]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100%[A]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100%[A]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: None
Supplement For Dialysis [Recommendation Level]: Pd
PD: None
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50, [D]
References
H&#246; ffler D, Koeppe P, Paeske B. Pharmacokinetics of azithromycin in normal and impaired renal function. Infection. 1995; 23: 356-61. [PMID: 8655206] / Lalak NJ, Morris DL. Azithromycin clinical pharmacokinetics. Clin Pharmacokinet. 1993; 25: 370-4. [PMID: 8287632]