Half-Life (Normalesrd) Hours
2 min/No data
Plasma Protein Binding %
No data
Volume Of Distribution L/Kg
0.25
Dose For Normal Renal Function
2.5-15 µg/kg/min
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
100% [D]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
100% [D]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: No data
Supplement For Dialysis [Recommendation Level]: Pd
PD: No dat
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50,titrate, [D]
References
Lawless CE, Loeb HS. Pharmacokinetics and pharmacodynamics of dobutamine. In: Chatterjee ED, ed. Dobutamine. New York: NCM Publishers; 1989: 33-47. / Majerus TC, Dasta JF, Bauman JL, Danziger LH, Ruffolo RR Jr. Dobutamine: ten years later. Pharmacotherapy. 1989; 9: 245-59. [PMID: 2671957]