Carteolol

General Toxicity Notes
Blood pressure is the best guide to dose and interval. Hyperkalemia in ESRD.
Excreted Unchanged %
>50
Half-Life (Normalesrd) Hours
7/33
Plasma Protein Binding %
20-30
Volume Of Distribution L/Kg
4.0
Dose For Normal Renal Function
0.5-10 mg q24h
Adjustment For Renal Failure Method
D
Adjustment For Renal Failure Gfr, Ml/Min >50 [Recommended Level]
100% [A]
Adjustment For Renal Failure Gfr, Ml/Min 10-50 [Recommended Level]
50% [A]
Adjustment For Renal Failure Gfr, Ml/Min <10 [Recommended Level]
25% [A]
Supplement For Dialysis [Recommendation Level]: Ihd
IHD: No data
Supplement For Dialysis [Recommendation Level]: Pd
PD: None
Supplement For Dialysis [Recommendation Level]: Crrt
CRRT: Dose for GFR 10-50,titrate, [D]
References
Amemiya M, Tabei K, Furuya H, Sakairi Y, Asano Y. Pharmacokinetics of carteolol in patients with impaired renal function. Eur J Clin Pharmacol. 1992; 43: 417-21. [PMID: 1451723] / Hasenfuss G, Sch&#246; fer-Korting M, Knauf H, Mutschler E, Just H. Pharmacokinetics of carteolol in relation to renal function. Eur J Clin Pharmacol. 1985; 29: 461-5. [PMID: 4092726]